Make no mistake, migraine is a potentially serious risk to health and wellbeing. First and foremost is the physical risk from having a full on migraine attack at the wrong time. For example driving a car in heavy traffic when the risk of losing control, or visual awareness of fast moving vehicles could lead to an accident. Similarly when alighting from vehicles in the roadway and in the presence of other close and fast moving traffic. The risks from prescribed or over the counter painkillers is no less alarming. Opiates can lead to dulled senses and poor memory around safe doses, leading to over dosing and loss of life as a result. Many reported instances of harm occurring from these means lead to the view that resort to pain killers in the absence of any definitive medical help from medications is a poor choice and best avoided. The possibility of targeted help from drugs or pills has recently taken a step backwards with the withdrawal of erenumab a new and much vaunted remedy now withdrawn by NICE.